Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane.

Journal of molecular medicine (Berlin, Germany) - 1 Jun 2010

Zampagni Mariagioia, Evangelisti Elisa, Cascella Roberta, Liguri Gianfranco, Becatti Matteo, Pensalfini Anna, Uberti Daniela, Cenini Giovanna, Memo Maurizio, Bagnoli Silvia, Nacmias Benedetta, Sorbi Sandro, Cecchi Cristina

Abstract excerpt

Increasing evidence indicates that cell surfaces are early interaction sites for Abeta-derived diffusible ligands (ADDLs) and neurons in Alzheimer's disease (AD) pathogenesis. Our previous data showed significant oxidative damage at the plasma membrane in fibroblasts from familial AD patients wit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Cholesterol

Share to Fibroblasts

Share to Lipid Peroxidation

Share to Membrane Microdomains

Share to Oxidation-Reduction

Source

Identifiers

PMID: 20217034
DOI: 10.1007/s00109-010-0603-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20217034-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane.PMID 20217034Read ↗

Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease.Semantic proximity Read ↗

Membrane cholesterol enrichment prevents Aβ-induced oxidative stress in Alzheimer's fibroblasts.Semantic proximity Read ↗

1-Palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine, an oxidized phospholipid, accelerates Finnish type familial gelsolin amyloidosis in vitro.Semantic proximity Read ↗

Oxidative stress up-regulates presenilin 1 in lipid rafts in neuronal cells.Semantic proximity Read ↗

Lipid rafts are the new Stress Granules regulatorsSemantic proximity Read ↗

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.Semantic proximity Read ↗

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.Semantic proximity Read ↗

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.Semantic proximity Read ↗

Preferred endocytosis of amyloid precursor protein from cholesterol-enriched lipid raft microdomainsSemantic proximity Read ↗

Ganglioside enriched phospholipid vesicles induce cooperative Aβ oligomerization and membrane disruptionSemantic proximity Read ↗

Localization of mature neprilysin in lipid rafts.Semantic proximity Read ↗

Cholesterol sensitivity of detergent resistance: a rapid flow cytometric test for detecting constitutive or induced raft association of membrane proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.