Article
Relationship of common candidate gene variants to electrocardiographic T-wave peak to T-wave end interval and T-wave morphology parameters.
Heart rhythm - 1 Jul 2010
Porthan Kimmo, Marjamaa Annukka, Viitasalo Matti, Väänänen Heikki, Jula Antti, Toivonen Lauri, Nieminen Markku S, Newton-Cheh Christopher, Salomaa Veikko, Kontula Kimmo, Oikarinen Lasse
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) in genes encoding cardiac ion channels and nitric oxide synthase-1 adaptor protein (NOS1AP) are associated with electrocardiographic (ECG) QT-interval duration, but the association of these SNPs with new, prognostically important ECG measures of ventricular repolarization is unknown. OBJECTIVE: The purpose of this study was to examine the relationship of SNPs to...
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