Article
A common variant near the KCNJ2 gene is associated with T-peak to T-end interval.
Heart rhythm - 1 Jul 2012
Marjamaa Annukka, Oikarinen Lasse, Porthan Kimmo, Ripatti Samuli, Peloso Gina, Noseworthy Peter A, Viitasalo Matti, Nieminen Markku S, Toivonen Lauri, Kontula Kimmo, Peltonen Leena, Havulinna Aki S, Jula Antti, O'Donnell Christopher J, Newton-Cheh Christopher, Perola Markus, Salomaa Veikko
Abstract excerpt
BACKGROUND: T-peak to T-end (TPE) interval on the electrocardiogram is a measure of myocardial dispersion of repolarization and is associated with an increased risk of ventricular arrhythmias. The genetic factors affecting the TPE interval are largely unknown. OBJECTIVE: To identify common genetic variants that affect the duration of the TPE interval in the general population. METHODS: We performed a genome-wide...
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