Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study.

doi:10.1080/07853890802392529

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Article

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study.

Annals of medicine - 1 Jan 2009

Raitakari Olli T, Blom-Nyholm Jaana, Koskinen Tuomas A, Kähönen Mika, Viikari Jorma S A, Lehtimäki Terho

Abstract excerpt

BACKGROUND: Common genetic variants in the nitric oxide synthase 1 adaptor protein gene (NOS1AP) and in the HERG potassium channel gene (KCNH2) have been associated with cardiac repolarization in middle-aged and elderly subjects. AIM: We examined the relation between these variants and QT interval duration in a population of healthy young adults. METHODS: We measured QT interval duration and genotyped rs10494366...

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PMID: 18785031
DOI: 10.1080/07853890802392529

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KCNH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study.PMID 18785031Read ↗

Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study.Semantic proximity Read ↗

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration.Semantic proximity Read ↗

Common candidate gene variants are associated with QT interval duration in the general population.Semantic proximity Read ↗

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations.Semantic proximity Read ↗

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.Semantic proximity Read ↗

Common variants at ten loci modulate the QT interval duration in the QTSCD Study.Semantic proximity Read ↗

Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study.Semantic proximity Read ↗

Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.Semantic proximity Read ↗

NOS1AP Polymorphisms Modify QTc Interval Duration But Not Cardiac Arrest Risk in Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA).Semantic proximity Read ↗

A common variant of NOS1AP is associated with QT interval duration in a Chinese population with Type 2 diabetes.Semantic proximity Read ↗

A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval.Semantic proximity Read ↗

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