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Article

NMR structure/function relationships of peptides corresponding to the C1B1 Region of PKC gamma.

Protein and peptide letters - 1 Jan 2010

Lauer Jason, Banerjee Debarshi, Shanks Denton, Dai Huaien, Gong Yu-Xi, Prakash Om, Takemoto Dolores

Abstract excerpt

The region (101-112) of C1B domain in PKC gamma plays a crucial role in the activation of the enzyme and subsequent gap junction inhibition. Substitution studies on peptides correlating to the C1B region show that a flexible structure and ability to be phosphorylated on serine 109 are critical for this purpose.

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Identifiers

PMID: 20214626
DOI: 10.2174/092986610789909485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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