Article
CK1δ kinase activity is modulated by protein kinase C α (PKCα)-mediated site-specific phosphorylation.
Amino acids - 1 May 2016
Meng Zhigang, Bischof Joachim, Ianes Chiara, Henne-Bruns Doris, Xu Pengfei, Knippschild Uwe
Abstract excerpt
Cellular signal transduction components are usually regulated not only on transcriptional or translational level, but also by posttranslational modifications. Among these, reversible phosphorylation represents the most abundant modification. In general, phosphorylation events are essential for regulating the activity of central signal transduction proteins, also including kinases itself. Members of the CK1 family...
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