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Article

Role of spastin in apical domain control along the rhabdomere elongation in Drosophila photoreceptor.

PloS one - 3 Mar 2010

Chen Geng, League Garrett P, Nam Sang-Chul

Abstract excerpt

BACKGROUND: Mutations in spastin are the most common cause of hereditary spastin paraplegia, a neurodegenerative disease. In this study, the role of spastin was examined in Drosophila photoreceptor development. METHODOLOGY/PRINCIPAL FINDINGS: The spastin mutation in developing pupal eyes causes a mild mislocalization of the apical membrane domain at the distal section, but the apical domain was dramatically...

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Identifiers

PMID: 20209135
DOI: 10.1371/journal.pone.0009480
PMCID: PMC2831062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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