Article

Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

2016-09-29

Abstract excerpt

Axons contain an endoplasmic reticulum (ER) network that is largely smooth and tubular, thought to be continuous with ER throughout the neuron, and distinct in form and function from rough ER; the mechanisms that form this continuous network in axons are not well understood. Mutations affecting proteins of the reticulon or REEP families, which contain intramembrane hairpin domains that can model ER membranes, caus...

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Literature Corpus work: ac00768c-6113-5b72-bbdf-a42159f9a194
DOI: 10.1101/069005

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