Article
Comprehensive analysis of MHC class I genes from the U-, S-, and Z-lineages in Atlantic salmon.
BMC genomics - 5 Mar 2010
Lukacs Morten F, Harstad Håvard, Bakke Hege G, Beetz-Sargent Marianne, McKinnel Linda, Lubieniecki Krzysztof P, Koop Ben F, Grimholt Unni
Abstract excerpt
BACKGROUND: We have previously sequenced more than 500 kb of the duplicated MHC class I regions in Atlantic salmon. In the IA region we identified the loci for the MHC class I gene Sasa-UBA in addition to a soluble MHC class I molecule, Sasa-ULA. A pseudolocus for Sasa-UCA was identified in the nonclassical IB region. Both regions contained genes for antigen presentation, as wells as orthologues to other genes...
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