Article
A nonclassical MHC class I U lineage locus in zebrafish with a null haplotypic variant.
Immunogenetics - 1 Sept 2015
Dirscherl Hayley, Yoder Jeffrey A
Abstract excerpt
Three sequence lineages of MHC class I genes have been described in zebrafish (Danio rerio): U, Z, and L. The U lineage genes encoded on zebrafish chromosome 19 are predicted to provide the classical function of antigen presentation. This MHC class I locus displays significant haplotypic variation and is the only MHC class I locus in zebrafish that shares conserved synteny with the core mammalian MHC. Here, we...
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