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Article

Modes of salmonid MHC class I and II evolution differ from the primate paradigm.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2001

Shum B P, Guethlein L, Flodin L R, Adkison M A, Hedrick R P, Nehring R B, Stet R J, Secombes C, Parham P

Abstract excerpt

Rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta) represent two salmonid genera separated for 15--20 million years. cDNA sequences were determined for the classical MHC class I heavy chain gene UBA and the MHC class II beta-chain gene DAB from 15 rainbow and 10 brown trout. Both genes are highly polymorphic in both species and diploid in expression. The MHC class I alleles comprise several highly...

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PMID: 11207285
DOI: 10.4049/jimmunol.166.5.3297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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