Article
Characterization of a divergent non-classical MHC class I gene in sharks.
Immunogenetics - 1 Apr 2003
Wang Carren, Perera Thushara V, Ford Heide L, Dascher Christopher C
Abstract excerpt
Sharks are the most ancient group of vertebrates known to possess members of the major histocompatibility complex (MHC) gene family. For this reason, sharks provide a unique opportunity to gain insight into the evolution of the vertebrate immune system through comparative analysis. Two genes encoding proteins related to the MHC class I gene family were isolated from splenic cDNA derived from spiny dogfish shark (...
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