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Article

The salmonid MHC class I: more ancient loci uncovered.

Immunogenetics - 1 Jul 2006

Miller Kristina M, Li Shaorong, Ming Tobi J, Kaukinen Karia H, Schulze Angela D

Abstract excerpt

An unprecedented level of sequence diversity has been maintained in the salmonid major histocompatibility complex (MHC) class I UBA gene, with between lineage AA sequence identities as low as 34%. The derivation of deep allelic lineages may have occurred through interlocus exon shuffling or convergence of ancient loci with the UBA locus, but until recently, no such ancient loci were uncovered. Herein, we document...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16794819
DOI: 10.1007/s00251-006-0125-2

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