Article
Standardized IMGT® Nomenclature of Salmonidae IGH Genes, the Paradigm of Atlantic Salmon and Rainbow Trout: From Genomics to Repertoires.
Frontiers in immunology - 1 Jan 2019
Magadan Susana, Krasnov Aleksei, Hadi-Saljoqi Saida, Afanasyev Sergey, Mondot Stanislas, Lallias Delphine, Castro Rosario, Salinas Irene, Sunyer Oriol, Hansen John, Koop Ben F, Lefranc Marie-Paule, Boudinot Pierre
Abstract excerpt
In teleost fish as in mammals, humoral adaptive immunity is based on B lymphocytes expressing highly diverse immunoglobulins (IG). During B cell differentiation, IG loci are subjected to genomic rearrangements of V, D, and J genes, producing a unique antigen receptor expressed on the surface of each lymphocyte. During the course of an immune response to infections or immunizations, B cell clones specific of...
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