Article
Extensive diversification of MHC in Chinese giant salamanders Andrias davidianus (Anda-MHC) reveals novel splice variants.
Developmental and comparative immunology - 1 Feb 2014
Zhu Rong, Chen Zhong-yuan, Wang Jun, Yuan Jiang-di, Liao Xiang-yong, Gui Jian-Fang, Zhang Qi-Ya
Abstract excerpt
A series of MHC alleles (including 26 class IA, 27 class IIA, and 17 class IIB) were identified from Chinese giant salamander Andrias davidianus (Anda-MHC). These genes are similar to classical MHC molecules in terms of characteristic domains, functional residues, deduced tertiary structures and genetic diversity. The majority of variation between alleles is found in the putative peptide-binding region (PBR),...
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