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Article

CYP2D6 polymorphism screening in a selected population of Spain (La Alpujarra): no effect of geographical isolation.

Annals of human biology - 1 Apr 2010

Fernández-Santander Ana, Luna Francisco, Santiago Catalina, Rodríguez María Teresa, Bandrés Fernando, Ruiz Jonatan R, Lucia Alejandro, Gómez-Gallego Félix

Abstract excerpt

BACKGROUND: There is growing interest in the CYP2D6 gene because of its key role in the metabolism of numerous commonly used drugs. AIM: We compared the frequency of the most frequent null CYP2D6 alleles (CYP2D6*3, CYP2D6*4,CYP2D6*5, CYP2D6*6, CYP2D6*7 and CYP2D6*8) between individuals from the Spanish population and from La Alpujarra. SUBJECTS AND METHODS: The present study comprises Spanish cohort (n = 185) and...

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PMID: 20205348
DOI: 10.1080/03014460903051658

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