Article
A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinoma.
The Journal of molecular diagnostics : JMD - 1 May 2010
Angulo Bárbara, García-García Elena, Martínez Rebeca, Suárez-Gauthier Ana, Conde Esther, Hidalgo Manuel, López-Ríos Fernando
Abstract excerpt
KRAS mutation testing has become a standard procedure in the management of patients with carcinomas. The most frequently used method for KRAS testing is direct sequencing of PCR products. The development of commercial real-time quantitative PCR kits offers a useful alternative since they are in t...
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