Article
Performance evaluation comparison of 3 commercially available PCR-based KRAS mutation testing platforms.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Mar 2014
Adams Julia A, Post Kristin M, Bilbo Sarah A, Wang Xiaoyan, Sen Joyashree D, Cornwell Anita J, Malek Amanda J, Cheng Liang
Abstract excerpt
The identification of KRAS mutations in patients with certain types of cancer, including colonic adenocarcinoma and non-small cell lung carcinoma, has become increasingly important as these patients are contraindicated from receiving epidermal growth factor receptor-targeted therapies. Several polymerase chain reaction (PCR)-based tests are commercially available for KRAS mutation testing including Applied...
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