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Article

Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling.

Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 2010

González-Pérez Vivian, Stack Katherine, Boric Katica, Naranjo David

Abstract excerpt

Propagation of the nerve impulse relies on the extreme voltage sensitivity of Na(+) and K(+) channels. The transmembrane movement of four arginine residues, located at the fourth transmembrane segment (S4), in each of their four voltage-sensing domains is mostly responsible for the translocation...

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Identifiers

PMID: 20194763
DOI: 10.1073/pnas.1000963107
PMCID: PMC2841883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20194763-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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