Molecular dynamics investigation of the ω-current in the Kv1.2 voltage sensor domains.

Abstract excerpt

Voltage sensor domains (VSD) are transmembrane proteins that respond to changes in membrane voltage and modulate the activity of ion channels, enzymes, or in the case of proton channels allow permeation of protons across the cell membrane. VSDs consist of four transmembrane segments, S1-S4, forming an antiparallel helical bundle. The S4 segment contains several positively charged residues, mainly arginines,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Electric Conductivity
• Share to Molecular Dynamics Simulation