Article
Methylation of H3K4 Is required for inheritance of active transcriptional states.
Current biology : CB - 9 Mar 2010
Muramoto Tetsuya, Müller Iris, Thomas Giles, Melvin Andrew, Chubb Jonathan R
Abstract excerpt
BACKGROUND: Maintenance of differentiation programs requires stability, when appropriate, of transcriptional states. However, the extent to which inheritance of active transcriptional states occurs from mother to daughter cells has not been directly addressed in unperturbed cell populations. RESULTS: By live imaging of single-gene transcriptional events in individual cells, we have directly recorded the potential...
Topics
- Cell Cycle
- Chromatin
- Dictyostelium
- Histones
- Methylation
- Mutation
- Transcription, Genetic