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Article

Variable number of tandem repeat polymorphisms of the interleukin-1 receptor antagonist gene IL-1RN: a novel association with the athlete status.

BMC medical genetics - 22 Feb 2010

Cauci Sabina, Di Santolo Manuela, Ryckman Kelli K, Williams Scott M, Banfi Giuseppe

Abstract excerpt

BACKGROUND: The interleukin-1 (IL-1) family of cytokines is involved in the inflammatory and repair reactions of skeletal muscle during and after exercise. Specifically, plasma levels of the IL-1 receptor antagonist (IL-1ra) increase dramatically after intense exercise, and accumulating evidence points to an effect of genetic polymorphisms on athletic phenotypes. Therefore, the IL-1 family cytokine genes are...

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Source

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Identifiers

PMID: 20175886
DOI: 10.1186/1471-2350-11-29
PMCID: PMC2837019

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Source receipt: pubmed, retrieved 7 Sept 2026.

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