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Article

Relevance of interleukin-1 receptor antagonist intron-2 polymorphism in ischemic stroke.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2003

Seripa Davide, Dobrina Aldo, Margaglione Maurizio, Matera Maria Giovanna, Gravina Carolina, Vecile Elena, Fazio Vito Michele

Abstract excerpt

Evidence of inflammatory phenomena associated with atherosclerotic plaques is extensive. Interleukin-1 (IL-1) is one of the key modulators of the inflammatory response, and its activity is critically regulated by its receptor antagonist (IL-1Ra). A variable number of tandem repeats (VNTR) in intron 2 of the human IL-1Ra shows a common polymorphism that has been related to different production of IL-1Ra and IL-1...

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Identifiers

PMID: 12686792
DOI: 10.1159/000069497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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