Article
A thiolate anion buried within the hydrocarbon ruler perturbs PagP lipid acyl chain selection.
Biochemistry - 23 Mar 2010
Khan M Adil, Moktar Joel, Mott Patrick J, Bishop Russell E
Abstract excerpt
The Escherichia coli outer membrane phospholipid:lipid A palmitoyltransferase PagP exhibits remarkable selectivity because its binding pocket for lipid acyl chains excludes those differing in length from palmitate by a solitary methylene unit. This narrow detergent-binding hydrophobic pocket buri...
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