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Article

Site-directed alkylation studies with LacY provide evidence for the alternating access model of transport.

Biochemistry - 15 Mar 2011

Jiang Xiaoxu, Nie Yiling, Kaback H Ronald

Abstract excerpt

In total, 59 single Cys-replacement mutants in helix VII and helix X of the lactose permease of Escherichia coli were subjected to site-directed fluorescence labeling in right-side-out membrane vesicles to complete the testing of Cys accessibility or reactivity. For both helices, accessibility/re...

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Identifiers

PMID: 21254783
DOI: 10.1021/bi101988s
PMCID: PMC3057939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21254783-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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