Article
Ig gene rearrangements on individual alleles of Abelson murine leukemia cell lines from (C57BL/6 x BALB/c) F1 fetal livers.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1991
Atkinson M J, Michnick D A, Paige C J, Wu G E
Abstract excerpt
We have previously shown that selection of Ig H chain V region genes used by colonies obtained from splenic B cells and fetal liver pre-B cells was dependent on strain-specific factors. Moreover, by examining the V gene usage in strains congenic at the Igh locus, we also determined that the strain-specific factor was encoded by sequences lying outside of the Igh locus. We decided to examine whether there are...
Topics
- Abelson murine leukemia virus
- Alleles
- Animals
- Blotting, Southern
- Cell Line
- DNA Probes
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, B-Lymphocyte, Light Chain
- Gestational Age
- Leukemia, Experimental