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A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild-derived and classical inbred mouse strains

2019-05-08

Abstract excerpt

<h4>ABSTRACT</h4> The genomes of classical inbred mouse strains include genes derived from all three major subspecies of the house mouse, Mus musculus . We recently posited that genetic diversity in the immunoglobulin heavy chain (IGH) gene loci of C57BL/6 and BALB/c mice reflect differences in subspecies origin. To investigate this hypothesis, we conducted high-throughput sequencing of IGH gene rearrangements t...

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Literature Corpus work
d3a3cba7-2958-5a61-95d0-e9776d9f7b92
DOI
10.1101/631754
Open publication

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A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild-derived and classical inbred mouse strainsDOI 10.1101/631754
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