Article
Germline diversity of the expressed BALB/c VhJ558 gene family.
Molecular immunology - 1 Jan 2001
Haines B B, Angeles C V, Parmelee A P, McLean P A, Brodeur P H
Abstract excerpt
Although the mouse immunoglobulin heavy chain (Igh) locus contains 15 heavy chain V (Vh) gene families, at least half of the Vh gene segments are members of the VhJ558 family. This large Vh gene family represents the least characterized germline coding regions of any of the mouse antigen receptor loci and the contribution of individual VhJ558 genes to the preimmune repertoire is poorly understood. In fact,...
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