Article
Allelic polymorphism of mouse Igh-J locus, which encodes immunoglobulin heavy chain joining (JH) segments.
Immunogenetics - 1 Jan 1992
Solin M L, Kaartinen M
Abstract excerpt
The mouse genome contains four functional JH genes, which encode immunoglobulin heavy chain joining segments. The JH gene cluster is located a few kilobases 5' from the constant region genes (C genes) on chromosome 12. The polymerase chain reaction (PCR)-technique was used to amplify DNA stretches from mouse genome of approximately 1,340 nucleotides in length containing all four JH genes (Igh-J locus). PCR...
Topics
- Alleles
- Animals
- Base Sequence
- Genes, Immunoglobulin
- Immunoglobulin Heavy Chains
- Immunoglobulin Joining Region
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic