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Article

eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 Feb 2010

Jiang Zhihong, Belforte Juan E, Lu Yuan, Yabe Yoko, Pickel James, Smith Carolyn Beebe, Je Hyun-Soo, Lu Bai, Nakazawa Kazu

Abstract excerpt

Protein synthesis inhibitor antibiotics are widely used to produce amnesia, and have been recognized to inhibit general or global mRNA translation in the basic translational machinery. For instance, anisomycin interferes with protein synthesis by inhibiting peptidyl transferase or the 80S ribosom...

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Identifiers

PMID: 20164343
DOI: 10.1523/JNEUROSCI.3971-09.2010
PMCID: PMC2836228

Genes

CA1
ATF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20164343-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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