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The molecular biology of mixed lineage leukemia

16 Jun 2009

Abstract excerpt

Mixed lineage leukemia is a very aggressive blood cancer that predominantly occurs in pediatric patients. In contrast to other types of childhood acute leukemias, mixed lineage leukemia presents with a dismal prognosis and despite the availability of advanced treatment methods cure rates have stagnated over the last years. Mixed lineage leukemia is characterized by the presence of MLL fusion proteins that are the...

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PMID: 19535349
DOI: 10.3324/haematol.2008.002436

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