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Article

Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.

Human molecular genetics - 15 May 2010

Lange Leslie A, Croteau-Chonka Damien C, Marvelle Amanda F, Qin Li, Gaulton Kyle J, Kuzawa Christopher W, McDade Thomas W, Wang Yunfei, Li Yun, Levy Shawn, Borja Judith B, Lange Ethan M, Adair Linda S, Mohlke Karen L

Abstract excerpt

Plasma homocysteine (Hcy) level is associated with cardiovascular disease and may play an etiologic role in vascular damage, a precursor for atherosclerosis. We performed a genome-wide association study for Hcy in 1786 unrelated Filipino women from the Cebu Longitudinal Health and Nutrition Surve...

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Source

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Identifiers

PMID: 20154341
DOI: 10.1093/hmg/ddq062
PMCID: PMC2860887

Genes

CPS1
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20154341-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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