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Article

Interactions between lifestyle and MTHFR polymorphisms on homocysteine concentrations in young adults belonging to the 1982 Pelotas Birth Cohort.

European journal of clinical nutrition - 1 Feb 2017

Oliveira I O, Silva L P, Borges M C, Cruz O M, Tessmann J W, Motta J V S, Seixas F K, Horta B L, Gigante D P

Abstract excerpt

BACKGROUND/OBJECTIVES: Homocysteine (Hcy) is a key intermediate in methionine metabolism. A high plasma concentration of Hcy is an independent risk factor for cardiovascular diseases among other determinants. In this study, we aimed to investigate the interactions between methylenetetrahydrofolate reductase enzyme gene (MTHFR) polymorphisms and lifestyle variables (smoking, alcohol intake and physical activity)...

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Identifiers

PMID: 27759072
DOI: 10.1038/ejcn.2016.193

Genes

MTHFR

Variants

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