Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ethosuximide reduces epileptogenesis and behavioral comorbidity in the <scp>GAERS</scp> model of genetic generalized epilepsy

6 Mar 2013

Abstract excerpt

PURPOSE: Ethosuximide (ESX) is a drug of choice for the symptomatic treatment of absence seizures. Chronic treatment with ESX has been reported to have disease-modifying antiepileptogenic activity in the WAG/Rij rat model of genetic generalized epilepsy (GGE) with absence seizures. Here we examined whether chronic treatment with ESX (1) possesses antiepileptogenic effects in the genetic absence epilepsy rats from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epilepsy research and treatment
Share to Genetics and Neurodevelopmental Disorders
Share to Glycogen Storage Diseases and Myoclonus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23464801
DOI: 10.1111/epi.12118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ethosuximide reduces epileptogenesis and behavioral comorbidity in the <scp>GAERS</scp> model of genetic generalized epilepsyPMID 23464801Read ↗

A genetic epilepsy rat model displays endophenotypes of psychosis.Semantic proximity Read ↗

Early treatment suppresses the development of spike-wave epilepsy in a rat model.Semantic proximity Read ↗

Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation.Semantic proximity Read ↗

Seizure expression, behavior, and brain morphology differences in colonies of Genetic Absence Epilepsy Rats from Strasbourg.Semantic proximity Read ↗

Gestational valproate exposure induces tissue-specific transcriptomic changes in the neonatal brain and choroid plexus in a rat model of epilepsy, GAERSSemantic proximity Read ↗

An Integrated Multi-Omic Network Analysis Identifies Seizure-Associated Dysregulated Pathways in the GAERS Model of Absence EpilepsySemantic proximity Read ↗

The impact of early-life environment on absence epilepsy and neuropsychiatric comorbiditiesSemantic proximity Read ↗

The Epigenetics of Epilepsy and Its ProgressionSemantic proximity Read ↗

Polygenic control of idiopathic generalized epilepsy phenotypes in the genetic absence rats from Strasbourg (GAERS).Semantic proximity Read ↗

Seizures in Mouse Models of Rare Neurodevelopmental Disorders.Semantic proximity Read ↗

Genetic models of absence epilepsy, with emphasis on the WAG/Rij strain of ratsSemantic proximity Read ↗

Genetic absence epilepsy rats from Strasbourg have increased corticothalamic expression of stargazin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.