Article
Innate immunity pathways and breast cancer Risk in African American and European-American women in the Women's Circle of Health Study (WCHS).
PloS one - 1 Jan 2013
Gong Zhihong, Quan Lei, Yao Song, Zirpoli Gary, Bandera Elisa V, Roberts Michelle, Coignet Jean-Gabriel, Cabasag Citadel, Sucheston Lara, Hwang Helena, Ciupak Gregory, Davis Warren, Pawlish Karen, Jandorf Lina, Bovbjerg Dana H, Ambrosone Christine B, Hong Chi-Chen
Abstract excerpt
African American (AA) women are more likely than European American (EA) women to be diagnosed with early, aggressive breast cancer. Possible differences in innate immune pathways (e.g., inflammatory responses) have received little attention as potential mechanisms underlying this disparity. We evaluated distributions of selected genetic variants in innate immune pathways in AA and EA women, and examined their...
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