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Article

Serum DNA can define tumor-specific genetic and epigenetic markers in gliomas of various grades

1 Feb 2010

Abstract excerpt

We evaluated whether cell-free circulating DNA can be used as a noninvasive approach for detection of genetic/epigenetic alterations in brain tumors during the course of the disease. Paired tumor-serum samples from 70 patients with either high-grade astrocytomas (n = 41) or oligodendrogliomas of various grades were analyzed. The median interval between surgery and serum sampling was 1 month (range 0.5-168...

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Identifiers

PMID: 20150384
DOI: 10.1093/neuonc/nop041

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