Article
Applications of cerebrospinal fluid circulating tumor DNA in the diagnosis of gliomas.
Japanese journal of clinical oncology - 9 Mar 2020
Zhao Zhenyu, Zhang Cheng, Li Mi, Shen Yiping, Feng Shiyu, Liu Jialin, Li Fangye, Hou Lei, Chen Zhong, Jiang Jingjing, Ma Xiaodong, Chen Ling, Yu Xinguang
Abstract excerpt
OBJECTIVE: The 2016 World Health Organization (WHO) Classification of Tumors of the Central Nervous System (CNS) was revised to include molecular biomarkers as diagnostic criteria. However, conventional biopsies of gliomas were spatially and temporally limited. This study aimed to determine whether circulating tumor DNA (ctDNA) from cerebrospinal fluid (CSF) could provide more comprehensive diagnostic information...
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