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Article

Correlation among pathology, genetic and epigenetic profiles, and clinical outcome in oligodendroglial tumors

3 Feb 2009

Abstract excerpt

Recent studies have revealed a correlation between specific genetic changes, such as loss of chromosome 1p and 19q, and sensitivity of oligodendroglial neoplasm to radiotherapy and chemotherapy; epigenetic changes also play an important role in some tumors. In this retrospective study, we analyzed chromosomal alterations in 17 loci and promoter methylation status of 8 tumor-related genes in 49 oligodendroglial...

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PMID: 19330828
DOI: 10.1002/ijc.24303

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