Article
Longitudinal assessment of genetic and epigenetic markers in oligodendrogliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2007
Lavon Iris, Zrihan Daniel, Zelikovitch Bracha, Fellig Yakov, Fuchs Dana, Soffer Dov, Siegal Tali
Abstract excerpt
PURPOSE: Because little is known about the evolution of genetic and epigenetic changes that occur during tumor progression in oligodendrogliomas, we evaluated these changes in paired early and progressive oligodendrogliomas. EXPERIMENTAL DESIGN: 1p36, 19q13, 10q22-26, and O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation status were assessed in 46 paired early and progressive oligodendrogliomas...
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