Article

Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers

2019-04-08

Abstract excerpt

<h4>SUMMARY</h4> Genome-wide DNA methylation profiling has shown that epigenetic abnormalities are biologically important in glioma and can be used to classify these tumors into distinct prognostic groups. Thus far, DNA profiling has required surgically resected glioma tissue; however, gliomas release tumoral material into biofluids, such as blood and cerebrospinal fluid, providing an opportunity for a minimally...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 22ec255b-b1d7-5c80-92c3-ae09dd3de559
DOI: 10.1101/601245

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markersDOI 10.1101/601245Read

A serum-based DNA methylation assay provides accurate detection of gliomaSemantic proximity Read

Alu methylation serves as a biomarker for non-invasive diagnosis of gliomaSemantic proximity Read

Detection of Circulating Tumor-specific DNA Methylation Markers in the Blood of Patients with Pituitary TumorsSemantic proximity Read

DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomasSemantic proximity Read

Detection of tumor-specific DNA methylation markers in the blood of patients with pituitary neuroendocrine tumorsSemantic proximity Read

Noninvasive detection of brain gliomas using plasma cell-free DNA 5-hydroxymethylcytosine sequencing.Semantic proximity Read

DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomasSemantic proximity Read

Prognostic and Predictive Biomarkers in Gliomas.Semantic proximity Read

DNA methylation profiling as a model for discovery and precision diagnostics in neuro-oncologySemantic proximity Read

cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnosticsSemantic proximity Read

Cerebrospinal fluid tumor DNA for liquid biopsy in glioma patients' management: Close to the clinic?Semantic proximity Read

An integrative analysis of genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA detects noninvasive diagnostic markers for gliomasSemantic proximity Read