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Article

p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas.

Neurosurgery - 1 Mar 2009

Wakabayashi Toshihiko, Natsume Atsushi, Hatano Hisashi, Fujii Masazumi, Shimato Shinji, Ito Motokazu, Ohno Masasuke, Ito Satoshi, Ogura Masatoshi, Yoshida Jun

Abstract excerpt

OBJECTIVE: Deoxyribonucleic acid (DNA) methylation of tumor origin can be detected in the serum/plasma of cancer patients. The aim of this study was to detect aberrant p16 promoter methylation as a potential diagnostic marker in the serum of patients with diffuse glioma to differentiate between g...

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Source

Identifiers

PMID: 19240607
DOI: 10.1227/01.NEU.0000340683.19920.E3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19240607-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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