Article
Long-range enhancers on 8q24 regulate c-Myc.
Proceedings of the National Academy of Sciences of the United States of America - 16 Feb 2010
Sotelo Jose, Esposito Dominic, Duhagon Maria Ana, Banfield Kelley, Mehalko Jennifer, Liao Hongling, Stephens Robert M, Harris Timothy J R, Munroe David J, Wu Xiaolin
Abstract excerpt
Recent genomewide association studies have found multiple genetic variants on chromosome 8q24 that are significantly associated with an increased susceptibility to prostate, colorectal, and breast cancer. These risk loci are located in a "gene desert," a few hundred kilobases telomeric to the Myc...
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