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Article

Lessons from functional analysis of genome-wide association studies.

Cancer research - 15 Jul 2013

Sur Inderpreet, Tuupanen Sari, Whitington Thomas, Aaltonen Lauri A, Taipale Jussi

Abstract excerpt

Most cancer-associated single-nucleotide polymorphisms (SNP) identified using genome-wide association studies are located outside of protein-coding regions, and their significance and mode of action have been a source of continuing debate. One proposed mechanism of action of the SNPs is that they would affect the activity of enhancer elements regulating critical target genes. In this review, we summarize recent...

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Source

Identifiers

PMID: 23832660
DOI: 10.1158/0008-5472.CAN-13-0789

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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