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Article

Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Mar 2010

David Sean P, Mezuk Briana, Zandi Peter P, Strong David, Anthony James C, Niaura Raymond, Uhl George R, Eaton William W

Abstract excerpt

INTRODUCTION: The 11q23.1 genomic region has been associated with nicotine dependence in Black and White Americans. METHODS: By conducting linkage disequilibrium analyses of 7 informative single nucleotide polymorphisms (SNPs) within the tetratricopeptide repeat domain 12 (TTC12)/ankyrin repeat and kinase containing 1 (ANKK1)/dopamine (D2) receptor gene cluster, we identified haplotype block structures in 270...

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Identifiers

PMID: 20133381
DOI: 10.1093/ntr/ntp201
PMCID: PMC2825103

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