Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

doi:10.1093/ntr/ntp064

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Article

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Jul 2009

Baker Timothy B, Weiss Robert B, Bolt Daniel, von Niederhausern Andrew, Fiore Michael C, Dunn Diane M, Piper Megan E, Matsunami Nori, Smith Stevens S, Coon Hilary, McMahon William M, Scholand Mary B, Singh Nanda, Hoidal John R, Kim Su-Young, Leppert Mark F, Cannon Dale S

Abstract excerpt

INTRODUCTION: Previous research revealed significant associations between haplotypes in the CHRNA5-A3-B4 subunit cluster and scores on the Fagerström Test for Nicotine Dependence among individuals reporting daily smoking by age 17. The present study used subsamples of participants from that study to investigate associations between the CHRNA5-A3-B4 haplotypes and an array of phenotypes not analyzed previously...

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Identifiers

PMID: 19436041
DOI: 10.1093/ntr/ntp064
PMCID: PMC2699926

Genes

CHRNA5

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Source receipt: pubmed, retrieved 7 Sept 2026.

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