Article
Genetic variability at IMPA2, INPP1 and GSK3β increases the risk of suicidal behavior in bipolar patients.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Nov 2013
Jiménez E, Arias B, Mitjans M, Goikolea J M, Roda E, Sáiz P A, García-Portilla M P, Burón P, Bobes J, Oquendo M A, Vieta E, Benabarre A
Abstract excerpt
Bipolar patients (BP) are at high risk of suicide. Causal factors underlying suicidal behavior are still unclear. However, it has been shown that lithium has antisuicidal properties. Genes involved in its putative mechanism of action such as the phosphoinositol and the Wnt/β-catenine pathways cou...
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