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Article

Genetic variability at IMPA2, INPP1 and GSK3β increases the risk of suicidal behavior in bipolar patients.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Nov 2013

Jiménez E, Arias B, Mitjans M, Goikolea J M, Roda E, Sáiz P A, García-Portilla M P, Burón P, Bobes J, Oquendo M A, Vieta E, Benabarre A

Abstract excerpt

Bipolar patients (BP) are at high risk of suicide. Causal factors underlying suicidal behavior are still unclear. However, it has been shown that lithium has antisuicidal properties. Genes involved in its putative mechanism of action such as the phosphoinositol and the Wnt/β-catenine pathways could be considered candidates for suicidal behavior (SB). Our aim was to investigate the association of the IMPA1 and 2,...

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Source

Identifiers

PMID: 23453640
DOI: 10.1016/j.euroneuro.2013.01.007

Genes

INPP1
IMPA2
IMPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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