Article
Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.
Journal of clinical immunology - 1 Nov 2010
Jiao Yu-Lian, Zhang Bing-Chang, You Li, Li Jian-Feng, Zhang Jie, Ma Chun-Yan, Cui Bin, Wang Lai-Cheng, Chen Zi-Jiang, Zhao Yue-Ran
Abstract excerpt
Accumulating evidences indicate that killer cell immunoglobulin-like receptors (KIRs) and their corresponding specific HLA-C ligands contribute to the pathogenesis of multiple autoimmune diseases via the modulation of natural killer (NK) cell and T cell functions. The present study was performed to investigate whether the polymorphism of KIR genes and HLA ligands associates with the susceptibility of ankylosing...
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