Article
Molecular analysis of APRT deficiency in mouse P19 teratocarcinoma stem cell line.
Somatic cell and molecular genetics - 1 Mar 1991
Cooper G E, DiMartino D L, Turker M S
Abstract excerpt
We have used four gene probes specific for mouse chromosome 8, including adenine phosphoribosyltransferase (aprt), to demonstrate that the P19 teratocarcinoma stem cell line contains two distinct chromosome 8 homologs. One represents the common laboratory mouse C3H (Mus musculus domesticus) homolog while the second homolog was presumably contributed by a feral Mus musculus musculus animal. Six cell lines with...
Topics
- Adenine Phosphoribosyltransferase
- Alleles
- Animals
- Blotting, Southern
- Chromosome Mapping
- DNA
- Electrophoresis, Agar Gel
- Gene Expression Regulation, Enzymologic
- Heterozygote
- Homozygote
- Mice
