Article
Spontaneous and ionizing radiation induced mutations involve large events when selecting for loss of an autosomal locus.
Mutation research - 1 Jul 1995
Turker M, Walker K A, Jennings C D, Mellon I, Yusufji A, Urano M
Abstract excerpt
The mouse P19H22 embryonal carcinoma cell line contains two distinct chromosome 8 homologs, one derived from Mus musculus domesticus (M. domesticus) and the other derived from Mus musculus musculus (M. musculus). It also contains a deletion for the M. musculus aprt allele, which is located on chromosome 8. In this study, cells with spontaneous or induced aprt deficiencies were isolated from P19H22 and examined to...
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