Spontaneous and ionizing radiation induced mutations involve large events when selecting for loss of an autosomal locus.

doi:10.1016/0027-5107(95)00046-l

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Article

Spontaneous and ionizing radiation induced mutations involve large events when selecting for loss of an autosomal locus.

Mutation research - 1 Jul 1995

Turker M, Walker K A, Jennings C D, Mellon I, Yusufji A, Urano M

Abstract excerpt

The mouse P19H22 embryonal carcinoma cell line contains two distinct chromosome 8 homologs, one derived from Mus musculus domesticus (M. domesticus) and the other derived from Mus musculus musculus (M. musculus). It also contains a deletion for the M. musculus aprt allele, which is located on chr...

Topics

Adenine Phosphoribosyltransferase
Alleles
Animals
Californium
Cesium Isotopes
Chromosome Deletion
DNA
DNA Mutational Analysis
Embryonal Carcinoma Stem Cells
Ethyl Methanesulfonate
Genetic Carrier Screening
Homozygote
Mice
Mutation
Neoplastic Stem Cells
Point Mutation
Tumor Cells, Cultured
Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 7603506
DOI: 10.1016/0027-5107(95)00046-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7603506-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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