Article
The E6 protein from vaccinia virus is required for the formation of immature virions.
Virology - 10 Apr 2010
Boyd Olga, Turner Peter C, Moyer Richard W, Condit Richard C, Moussatche Nissin
Abstract excerpt
An IPTG-inducible mutant in the E6R gene of vaccinia virus was used to study the role of the E6 virion core protein in viral replication. In the absence of the inducer, the mutant exhibited a normal pattern DNA replication, concatemer resolution and late gene expression, but it showed an inhibition of virion structural protein processing it failed to produce infectious particles. Electron microscopic analysis...
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